Starting young, he restored furniture throughout his high-school years. Shortly after, he was trained as a cabinet maker at The John Makepeace School for Craftsmen in Wood in 1985 before studying Design at the Royal College of Art in London. Come the late 1980s, Grcic worked at one of London's most prominent design stores, SCP. He describes his time in this environment describing :"... his experiences in England as stirring his creative potential."

He set up his own office in Munich, Germany in 1991. Today, Konstantin Grcic Design GmbH is based in Berlin. The office is active in several fields ranging from industrial design projects, exhibition design and architectural collaborations. Amongst his renowned clients are Aeance, Authentics, Cassina, ClassiCon, Flötotto, Flos, Galerie Kreo, Kettal, Laufen, Magis, Muji, Nespresso, Plank, Smart and Vitra.

He is the recipient of numerous awards such as the Compasso d`Oro for his MAYDAY lamp (Flos, 2001), the MYTO chair (Plank, 2011) and the OK lamp (Flos 2016). Work by Konstantin Grcic forms part of the permanent collections of the world´s most important design museums (a.o. MoMA/New York, Centre Georges Pompidou/Paris).

Grcic defines function in human terms, combining formal strictness with considerable mental acuity and humor. His work is characterized by a careful research into the history of art, design and architecture and his passion for technology and materials. A defining style of his pieces are geometric shapes, unexpected angles, and hard edges. 

Grcic's creations emphasize his focus on usability, his favorite objects to develop are chairs, stating "Designing chairs touches issues of society, how we live...How life changes - that’s most interesting." His portfolio of objects ranges between umbrellas, lighting, furniture, tableware, espresso makers, and watches. Some of his more well known pieces include the 1998 Mayday lamp, 1999 ES shelf and 2001 Chaos chair. 

More recently, his ventures in mass-production have required the use of 3D modeling software and high-tech ceramics. The Myto Chair was award-winning at the 2008 Milan Furniture Fair, with it's advanced engineered plastics. However, Grcic also uses simpler design processes such as constructing paper models, his methodology consisting of extensive research.